Accurate 25-OH Vitamin D Assessment with Poclight CLIA Assays

1. Why 25-OH Vitamin D Matters

The main physiological role of vitamin D and its metabolites is to maintain normal blood calcium and phosphorus levels, to ensure bone health and normal neuromuscular function.

25-Hydroxy Vitamin D is the main storage form of vitamin D in the human body, and the detection of serum 25-Hydroxy VD level has been recognized as the most reasonable indicator to reflect the status of vitamin D.

Clinically, 25-hydroxyvitamin D is the preferred indicator because:

● It reflects combined effects of sunlight, diet, and supplements

● It is stable in serum and plasma

● It reliably shows long-term vitamin D reserves

Inadequate vitamin D can contribute to:

● Reduced bone density and greater fracture risk

● Muscle weakness and higher fall likelihood

● Impaired immune function

● Seasonal fatigue or malaise

2.  Reference Value for Vitamin D

Levels of 50 nmol/L (20 ng/mL) or more are sufficient for most people.

Optimal serum concentrations of 25(OH)D for bone and general health have not been established because they are likely to vary by stage of life, by race and ethnicity, and with each physiological measure used.

In addition, although 25(OH)D levels rise in response to increased vitamin D intake, the relationship is nonlinear. The amount of increase varies, for example, by baseline serum levels and duration of supplementation.

Understanding these dynamics highlights the importance of accurate, reliable measurement of 25(OH)D, precisely what our Poclight 25-OH VD assay is designed to provide.

3.  Poclight 25-OH VD Assay Key Features

1. LOD: 3ng/mL
2. Linearity: 3-70ng/mL, in this linear range, the linear correlation coefficient "r" is not less than 0.9900
3. Repeatability: CV<5% 
4. Exceptional Speed: Reduces the detection time from 3 hours to just 10 minutes.
5. Compatible with Poclight C5000 Benchtop CLIA Analyzer

Operation process

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